7 Crucial Differences between Antigen and Antibody with Comparison Table

What is the difference between antigen and antibody?

The human body has both natural and innate immunological responses against pathogens. The response helps to fight the buildup of pathogens in the body.

These two terms antigen and antibody tend to confuse a lot of people not only students pursuing their biological studies.

The main difference between antigen and antibody is that the former is a foreign substance that induces the immune response and the latter is a protein that detects and binds foreign substances in the body.

The lesson provides the difference between antigen and antibody in tabular form as well as point form of easier understanding.

Differences between Antigen and Antibody

What Is An Antigen?

An antigen is a substance that stimulates the body to produce antibodies. It is simply a foreign substance the body gets exposed to and it can cause some sicknesses.

Examples of antigens are bacteria, viruses, and fungi. They have the reputation of causing infection in the body.

What Is An Antibody?

An antibody Y-shaped protein molecules manufactured by the body to help fight foreign substances causing diseases. Antibodies are also known as immunoglobulins.

They are naturally produced by the body and they occur in almost all cells in the body to offer protection against antigens.

Comparison Chart: Antigen Vs Antibody

Basic TermsAntigenAntibody
MeaningIs a foreign substance that induces the immune responseIs a protein that detects and bind foreign substances in the body
Molecule TypeLipids, nucleic acid, polysaccharidesProteins
OriginFormed within the body and can also be induced externallyFormed within the body only
Binding siteEpitopeParatope
EffectCauses disease in the bodyProtect the body against foreign materials
KindsThree types as Exogenous, Endogenous and AutoantigensFour kinds such as Immunoglobulins M, G, E, D and A
PrevalenceExist in all types of cellsExist in specific types of cells

Core Differences between Antibody and AntigenĀ 

  1. Antigen triggers the immune system to release antibodies while antibodies help to bind antigens in the body.
  2. Antibodies are proteins in nature whereas antigens can be proteins, lipids, or carbohydrates
  3. Antigen causes diseases or allergic reactions whereas antibodies protect the body by immobilizing antigen materials.
  4. The antigen is of three kinds as Exogenous, Endogenous, and Autoantigens while antibodies are of five kinds such as Immunoglobulins M, G, E, D and A

Comparison Video

Conclusion

Examples of antigens are bacteria, viruses, and fungi while antibodies are B lymphocytes. This is the core difference between antigen and antibody. Use the comment section to share your views and suggestions.

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