Difference between Cytoplasm and Protoplasm

What is the difference between cytoplasm and protoplasm?

A cell is responsible for the existence of life. It tends to contain cytoplasm, protoplasm, cell membrane and genetic materials among many other things.

The main difference between cytoplasm and protoplasm is that Cytoplasm is the fluid that consists of all of the contents outside of the nucleus and enclosed within the cell membrane of a cell whereas Protoplasm is the colourless material consisting of the living part of a cell, including the cytoplasm, nucleus, and other organelles.

The lesson provides the core difference between cytoplasm and protoplasm in short points as well as a tabular form for easier understanding.

Read More: Difference between Cytoplasm and Nucleoplasm 

Difference between Cytoplasm and Protoplasm

What Is Cytoplasm?

The cytoplasm is a transparent material present between the cell membrane and the nucleus of the eukaryotic cell.

The main components of the cytoplasm are cell organelles, metabolic wastes, proteins, and food reserves. It tends to be semi-fluid and transparent in nature.

The cytoplasm normally surrounds the nucleus and it contains both cytosol and cytoplasmic matrix. This substance helps to differentiate between outer ectoplasm and inner endoplasm.

What Is Protoplasm?

Protoplasm is a jelly-like substance where biological activities take place in a cell. The main constituents of protoplasm are 90% water, salts, proteins, lipids, and carbohydrates.

The main features of protoplasm are selective permeability, elastic, granular, colloidal, and colourless substance.

Comparison Chart: Cytoplasm Vs Protoplasm

Basic TermsCytoplasm Protoplasm
DefinitionIt is a semi-solid material found between the nucleus and cell membraneIt is a jelly-like substance that surrounds the cytoplasm, nucleus and cell membrane
Core Structural DifferenceContain Golgi body, Endoplasmic reticulum, Mitochondria, Ribosomes, LysosomesContain cytoplasm and nucleus
Main componentsWater, metabolic wastes, proteins, food reserves.Proteins, lipids, carbohydrates, nucleic acid and inorganic salts.
Modern PerceptionRelevantObsolete

Main Difference between Cytoplasm and Protoplasm

  1. The cytoplasm is a semi-solid material present between the nucleus and cell membrane while protoplasm is a jelly-like substance that surrounds the nucleus and cytoplasm
  2. Main organelles in the cytoplasm are Golgi body, Mitochondria, Endoplasmic reticulum, Lysosomes, and Ribosomes while protoplasm is cytoplasm and nucleus.

Read More: Difference between Cytosol and Cytoplasm 

Comparison Video



The fact remains that both nucleus and cytoplasm help to make up protoplasm. The core difference between the cytoplasm and protoplasm brainly above is quite simple to comprehend.

More Sources and References

  • https://byjus.com/biology/difference-between-cytoplasm-and-protoplasm/
  • https://www.vedantu.com/biology/difference-between-cytoplasm-and-protoplasm
  • https://study.com/academy/answer/what-are-the-differences-between-cytoplasm-and-protoplasm.html 
  • https://en.wikipedia.org/wiki/Protoplasm
  • https://www.britannica.com/science/protoplasm 

Leave a Comment